14
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8433 | HQNO | Mitochondrial Metabolism | |
HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species. | |||
T22381 | Antimalarial agent 14 | 4-hydroxy-3-phenyl-naphthalene-1,2-dione,2-Hydroxy-3-phenyl-1,4-naphthoquinone | Others |
Antimalarial agent 14 (NSC-102533) is a bioactive chemical. | |||
T19714 | Fenpyroximate | Others | |
Fenpyroximate is an acaricide and insecticide. It blocking the mitochondrial electron transport in complex I. | |||
T5300 | Ammonium formate | Formic acid ammonium salt | Others |
Ammonium formate (Formic acid ammonium salt) is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport... | |||
T5337 | IACS-010759 | IACS-10759,IACS 10759,IACS10759 | Apoptosis , Others , Mitochondrial Metabolism |
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain. | |||
T2970 | Rotenone | Rotenon,Paraderil,Barbasco,Rotocide,Dactinol | Apoptosis , Dehydrogenase , Mitochondrial Metabolism , p53 , Autophagy |
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces... | |||
T5114 | Pyridaben | Calcium Channel , Parasite | |
Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria). | |||
T27516 | GW844520 | ||
GW844520 is a potent and selective inhibitor of the cytochrome bc1 complex of mitochondrial electron transport in P. falciparum. | |||
T35040 | Vatiquinone | EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743 | |
Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, o... | |||
T37519 | Diquat (bromide) | ||
Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1Diquat administra... | |||
T79636 | PKM2-IN-4 | ||
Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial H2O2 production rate and electron transport system coupling [... | |||
T35860 | AP39 | ||
AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an ... | |||
T37498 | Antimycin A4 | ||
Antimycin A4 is an active component of the antimycin A antibiotic complex that is more polar than antimycin A1 , antimycin A2 , and antimycin A3 . Antimycin A4 inhibits ATP-citrate lyase with a Ki value of 64.8 μM. The a... | |||
T37692 | Piericidin B | ||
Piericidin B is a bacterial metabolite that has been found inS. mobaraensisand has insecticidal and antimicrobial activities.1,2,3It inhibits NADH oxidase activity in isolated bovine heart mitochondria and inhibits respi... |